HPLC Determination of Biperiden in Solid Dosage Forms

A rapid, new analytical method, based on liquid chromatography with UV detection, has been developed and utilised for the determination of biperiden hydrochloride in solid dosage forms. The chromatographic separation was performed a conventional C18 reversed phase column mobile composed acetonitrile-buffer mixture. Ultraviolet detection carried out at 205 nm. rapid extraction procedure using ultrasonic bath obtained good yield values analyte (≥ 98.4%). method specifically routine analysis forms applicable concentration range. linearity range investigated assay is between 2–6 μg mL−1. selective sufficiently precise. Thus, suitable biperiden.